A protein-only RNase P in human mitochondria.

Walker, Scott C; Engelke, David R · Cell · 2008

basic_science · Level V

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Abstract

In bacteria, archaea, and the eukaryote nucleus, the endonuclease ribonuclease P (RNase P) is composed of a catalytic RNA that is assisted by protein subunits. Holzmann et al. (2008) now provide evidence that the human mitochondrial RNase P is an entirely protein-based enzyme.

Medical subject headings