Myosin learns to recruit AMPA receptors.

Perlson, Eran; Holzbaur, Erika L F · Cell · 2008

basic_science · Level V

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Abstract

The induction of long-term potentiation (LTP) leads to an increase in the density of AMPA receptors at dendritic spines. New work by Wang et al. (2008) reveals the mechanism by which myosin Vb regulates the intracellular trafficking of AMPA receptors from recycling endosomes to synaptic sites during LTP.

Medical subject headings