Knockdown screens to knockout HIV-1.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18984154.
- Also identified by DOI 10.1016/j.cell.2008.10.007 and PMC identifier 3598618.
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Abstract
Three recent screens use siRNAs to identify host genes that are critical for HIV-1 replication. These screens have uncovered hundreds of human genes not previously known to be commandeered by the virus during infection. Although some caveats remain, this screening approach opens up a new landscape of viral-host interactions for future exploration.
Medical subject headings
- HIV-1
- Virus Replication