Selection of oligonucleotides for whole-genome microarrays with semi-automatic update.

Golfier, G; Lemoine, S; van Miltenberg, A; Bendjoudi, A; Rossier, J; Le Crom, S; Potier, M-C · Bioinformatics · 2009

basic_science · Level V

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Abstract

Oligonucleotide microarray probes are designed to match specific transcripts present in databases that are regularly updated. As a consequence probes should be checked every new database release. We thus developed an informatics tool allowing the semi-automatic update of probe collections of long oligonucleotides and applied it to the mouse RefSeq database. http://www.bio.espci.fr/sol/

Medical subject headings