Reversal of opioid-induced gastric dysfunction in a critically ill burn patient after methylnaltrexone.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 19020145.
- Also identified by DOI 10.1213/ane.0b013e31818556d3.
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Abstract
Peripheral-acting mu opiate receptor antagonists have been extensively studied for the treatment of opiate-induced constipation in advanced illness for the prophylaxis of postoperative ileus. We document the first intensive care patient to receive methylnaltrexone in an attempt to facilitate enteral nutrition. Gastric residuals markedly decreased and enteral feeding increased after administration of i.v. methylnaltrexone. The patient's ileus resolved coincident with the first injection.
Medical subject headings
- Analgesics, Opioid
- Burns
- Gastric Emptying
- Naltrexone
- Narcotic Antagonists