Sirolimus ameliorated post lung transplant chylothorax in lymphangioleiomyomatosis.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 19021963.
- Also identified by DOI 10.1016/j.athoracsur.2008.07.062.
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Abstract
We report a successful case of sirolimus treatment for chylous pleural and peritoneal effusions of lymphangioleiomyomatosis after lung transplantation. A 32-year-old woman underwent living donor lung transplantation. Persistent chylous pleural and peritoneal effusions were seen postoperatively. Pleurodesis by intrathoracic injection of OK-432, minomycin, and somatostatine analog failed to control chylous effusions. However, sirolimus treatment reduced the amount of chylous drainage and improved both chylous pleural and peritoneal effusions.
Medical subject headings
- Chylothorax
- Chylous Ascites
- Immunosuppressive Agents
- Lung Transplantation
- Sirolimus