The effect of topical nitroglycerin on transcutaneous oxygen.

Romanelli, M; Katz, M H; Alvarez, A F; Eaglstein, W H; Falanga, V · Br J Dermatol · 1991

other · Level V

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Abstract

The use of topical nitroglycerin has been reported to aid the healing of chronic skin ulcers. In this study, the effect of 2% nitroglycerin ointment on transcutaneous oxygen pressure (TcPO2) was investigated in skin adjacent to the area of ointment application. Topical nitroglycerin caused a two-fivefold decrease in TcPO2 in skin next to or up to 9 cm away from the site of application of the ointment.

Medical subject headings