Lighting up the stressed ER.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19041740.
- Also identified by DOI 10.1016/j.cell.2008.11.004 and PMC identifier 3117787.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Balancing the capacity for protein maturation with changes in protein flux through the endoplasmic reticulum (ER) is crucial for maintaining ER homeostasis. In this issue, Merksamer et al. (2008) exploit a redox-sensitive fluorescent protein to monitor the environment inside the ER of living yeast, illuminating how this organelle responds to different perturbations.
Medical subject headings
- Endoplasmic Reticulum
- Protein Folding
- Saccharomyces cerevisiae