Evolution in a test tube: the hatchet before the scalpel.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19041741.
- Also identified by DOI 10.1016/j.cell.2008.11.005.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Gene duplication provides an organism with a rich source of genetic material for tinkering by selection during evolution. In this issue, Rancati et al. (2008) report that extensive polyploidy and aneuploidy are the initial evolutionary changes in yeast selected in vitro to overcome defects resulting from the loss of a myosin II protein crucial for normal cytokinesis.
Medical subject headings
- Directed Molecular Evolution
- Saccharomyces cerevisiae