Polarity and differential inheritance--universal attributes of life?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19041746.
- Also identified by DOI 10.1016/j.cell.2008.11.006 and PMC identifier 2844324.
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Abstract
When and why did cell polarization arise? Recent work in bacteria and yeast suggests that polarization may have evolved to restrict senescence to one daughter during division by enabling the differential segregation of damaged material. In more complex organisms, polarity functions have diversified to permit the differential inheritance of centrosomes, RNAs, proteins, and membranes, which is essential for the generation of diverse cell types from stem cells and for morphogenesis.
Medical subject headings
- Cell Division
- Cell Polarity