A gut feeling for obesity: 7TM sensors on enteroendocrine cells.

Engelstoft, Maja S; Egerod, Kristoffer L; Holst, Birgitte; Schwartz, Thue W · Cell Metab · 2008

Level V

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Abstract

Enteroendocrine cells, which secrete peptide hormones in response to sensation of food and gut microbiota products, can now be genetically tagged, isolated, cultured, and characterized for expression of the elusive chemosensors, as shown in publications in PNAS (Samuel et al., 2008) and in this issue (Reimann et al., 2008).

Medical subject headings