Killer granzyme B linked to N-myc- and c-myc-dependent HSC survival: isn't that comyc?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19041771.
- Also identified by DOI 10.1016/j.stem.2008.11.003.
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Abstract
c-myc is a key regulator of hemopoietic stem cell (HSC) activity. In this issue of Cell Stem Cell, Laurenti et al. (2008) show that c-myc and N-myc control HSC survival and link this finding to the regulation of granzyme B expression.
Medical subject headings
- Gene Expression Regulation, Enzymologic
- Granzymes
- Hematopoietic Stem Cells
- Proto-Oncogene Proteins c-myc