Have hair follicle stem cells shed their tranquil image?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19041772.
- Also identified by DOI 10.1016/j.stem.2008.11.005.
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Abstract
In a recent issue of Nature Genetics, Jaks et al. (2008) demonstrate that hair follicle cells expressing the intestinal stem cell marker Lgr5 are hair follicle epithelial stem cells. In contrast to the established bulge stem cell population, Lrg5(+) cells are actively cycling and reside in part outside the bulge.
Medical subject headings
- Adult Stem Cells
- Cell Lineage
- Epithelial Cells
- Hair Follicle
- Receptors, G-Protein-Coupled