Raptor swoops in on metabolism.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 19046565.
- Also identified by DOI 10.1016/j.cmet.2008.10.007.
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Abstract
The mammalian target of rapamycin (mTOR) serine/threonine kinase plays a central role in insulin signaling and cell growth, through two distinct complexes with its subunits raptor or rictor. In this issue, two reports utilizing tissue-specific knockout mice detail key roles for mTORC1 in skeletal muscle and adipose tissue function.
Medical subject headings
- Adipose Tissue
- Carrier Proteins
- Muscle, Skeletal
- Transcription Factors