Surface engineering of poly(D,L-lactic acid) by entrapment of soluble eggshell membrane protein.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19048638.
- Also identified by DOI 10.1002/jbm.a.32304.
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Abstract
Soluble eggshell membrane protein (SEP) is used to engineer poly(D,L-lactic acid) (PDL-LA) membrane surface by a physical entrapment method to enhance cytocompatibility. Attenuated total reflection Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and contact angle measurements are used to characterize SEP-modified PDL-LA membrane surface and confirm the formation of an even and stable layer of SEP on PDL-LA membrane surface. NIH3T3 cell lines are used as model cells to evaluate cytocompatibility of the SEP-modified PDL-LA membrane, which is much better than that of virgin PDL-LA membrane. The enhanced cytocompatibility facilitates potential application in tissue engineering.
Medical subject headings
- Biocompatible Materials
- Lactic Acid
- Polymers
- Protein Engineering