Intrabronchial foreign body extracted with tranilast and corticosteroid.
case_report · Level V
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- Record sourced from PubMed, PMID 19049780.
- Also identified by DOI 10.1016/j.athoracsur.2008.04.060.
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Abstract
We present a case of intrabronchial foreign body buried in granulation tissue, which was successfully extracted administrating tranilast (n-[3,4-dimethoxycinnamoyl] anthranilic acid), suppressing collagen synthesis by fibroblasts in keloid and hypertrophic scars, and corticosteroid. Bronchoscopy of a 74-year-old man showed the nail was buried in reactive granulation tissue and could not be observed from the surface. Tranilast at 300 mg/day and methylprednisolone at 250 mg/day were prescribed for 4 days, followed by a reduction of the corticosteroid to 40 mg/day for 3 days. Seven days later, the granulation tissue and mucosal edema were diminished, and the nail was successfully extracted.
Medical subject headings
- Bronchi
- Foreign Bodies
- Granulation Tissue
- Methylprednisolone
- ortho-Aminobenzoates