Toll-like receptors and cancer.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19052556.
- Also identified by DOI 10.1038/nrc2541.
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Abstract
Toll-like receptors (TLRs) are a family of pattern recognition receptors that are best-known for their role in host defence from infection. Emerging evidence also suggests that TLRs have an important role in maintaining tissue homeostasis by regulating the inflammatory and tissue repair responses to injury. The development of cancer has been associated with microbial infection, injury, inflammation and tissue repair. Here we discuss how the function of TLRs may relate to these processes in the context of carcinogenesis.
Medical subject headings
- Cell Transformation, Neoplastic
- Neoplasm Proteins
- Neoplasms
- Toll-Like Receptors