Counting motors by force.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19070567.
- Also identified by DOI 10.1016/j.cell.2008.11.021.
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Abstract
Properties of the microtubule motor protein kinesin-1 have been well characterized in vitro but not in the viscous environment of a cell. By measuring the force that kinesin-1 exerts on lipid droplets in fly embryos, Shubeita et al. (2008) determine the number of active motors per droplet and find unexpected differences between motor regulation in vivo and in vitro.
Medical subject headings
- Drosophila
- Lipid Metabolism
- Optics and Photonics