Divided within: heterogeneity within adult stem cell pools.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19070570.
- Also identified by DOI 10.1016/j.cell.2008.11.034.
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Abstract
In this issue, Wilson et al. (2008) demonstrate that there are two functional subsets of hematopoietic stem cells that have distinctive kinetics of cell cycling. They present evidence that cells may transition between the two kinetic states, establishing one subpopulation that is ready to proliferate and another that is a deeply quiescent reserve.
Medical subject headings
- Adult Stem Cells
- Hematopoietic Stem Cells