In situ assembly of linked geometrically coupled microdevices.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19074262.
- Also identified by DOI 10.1073/pnas.0808808105 and PMC identifier 2629335.
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Abstract
Complex systems require their distinct components to function in a dynamic, integrated, and cooperative fashion. To accomplish this in current microfluidic networks, individual valves are often switched and pumps separately powered by using macroscopic methods such as applied external pressure. Direct manipulation and control at the single-device level, however, limits scalability, restricts portability, and hinders the development of massively parallel architectures that would take best advantage of microscale systems. In this article, we demonstrate that local geometry combined with a simple global field can not only reversibly drive component assembly but also power distinct devices in a parallel, locally uncoupled, and integrated fashion. By employing this single approach, we assemble and demonstrate the operation of check valves, mixers, and pistons within specially designed microfluidic environments. In addition, we show that by linking these individual components together, more complex devices such as pumps can be both fabricated and powered in situ.
Medical subject headings
- Microfluidic Analytical Techniques
- Microfluidics