POLAR MAPPER: a computational tool for integrated visualization of protein interaction networks and mRNA expression data.

Gonçalves, Joana P; Grãos, Mário; Valente, André X C N · J R Soc Interface · 2009

other · Level V

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Abstract

Polar Mapper is a computational application for exposing the architecture of protein interaction networks. It facilitates the system-level analysis of mRNA expression data in the context of the underlying protein interaction network. Preliminary analysis of a human protein interaction network and comparison of the yeast oxidative stress and heat shock gene expression responses are addressed as case studies.

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