Here comes the sun: recognition of UV-damaged DNA.

Chu, Gilbert; Yang, Wei · Cell · 2008

basic_science · Level V

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Abstract

The first step in the repair of DNA damage is lesion detection. In this issue, Scrima et al. (2008) report the structure of the complex of DNA Damage-Binding Protein 1 (DDB1) and DDB2 bound to a DNA photodimer, providing critical insight into the repair of DNA damage caused by ultraviolet light.

Medical subject headings