Search for serum biomarkers associated with abdominal aortic aneurysm growth--a pilot study.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 19111482.
- Also identified by DOI 10.1016/j.ejvs.2008.11.014.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Serological biomarkers could reflect asymptomatic infrarenal aortic aneurysm (AAA) activity and guide patient management. Serum concentrations of C-reactive protein (CRP), alpha 1-antitrypsin and lipoprotein(a) were measured in blood samples from 35 AAA patients and 35 controls and correlated with the aortic diameter and AAA growth in the previous 12 months. We found a positive correlation between CRP and AAA diameter (r=0.46; p=0.007) and alpha 1-antitrypsin and AAA growth (r=0.55; p=0.004). Alpha 1-antitrypsin may be a promising biomarker of AAA growth.
Medical subject headings
- Aortic Aneurysm, Abdominal
- C-Reactive Protein
- Lipoprotein(a)
- alpha 1-Antitrypsin