The liver--a potential new player in islet regeneration?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19117540.
- Also identified by DOI 10.1016/j.cmet.2008.12.009.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Pancreatic islet beta cell mass expands in response to certain physiological conditions such as pregnancy and obesity, but the signaling pathways involved are not well understood. Possible insights come from a newly described regulatory circuit through which obesity-enhanced kinase signaling in the liver triggers expansion of islet mass and enhanced insulin secretion.
Medical subject headings
- Insulin-Secreting Cells
- Islets of Langerhans
- Liver
- Regeneration