Antidepressants on trial: how valid is the evidence?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19118316.
- Also identified by DOI 10.1192/bjp.bp.108.054767.
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Abstract
A recent meta-analysis concluded that newer antidepressant drugs are equivalent to or no better than placebos, a conclusion at some variance with their commonly judged clinical effectiveness. The 'disconnect' between randomised controlled trials and clinical practice would benefit from dissection of contributing factors, and redressing limitations to current trial procedures.
Medical subject headings
- Antidepressive Agents
- Depressive Disorder