Acquired cutis laxa associated with heavy chain deposition disease.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 19119136.
- Also identified by DOI 10.1016/j.jaad.2008.05.007.
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Abstract
Acquired cutis laxa (generalized acquired elastolysis) is a condition of unknown etiology characterized by a degeneration of elastic fibers in the skin, resulting in laxity with reduced elastic recoil. We describe a patient with acquired cutis laxa associated with an underlying heavy chain deposition disease. Direct immunofluorescence testing of lesional skin demonstrated immunoglobulin G deposition on elastic fibers, suggesting that in some cases, cutis laxa may have an immune-mediated etiopathogenesis.
Medical subject headings
- Cutis Laxa
- Heavy Chain Disease
- Immunoglobulin G
- Skin