Hematopoietic stem cell quiescence: yet another role for p53.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19128788.
- Also identified by DOI 10.1016/j.stem.2008.12.007.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
p53, sometimes referred to as the "guardian of the genome," helps regulate cell-cycle arrest, DNA-damage repair, apoptosis, and senescence. Adding to this list, in this issue of Cell Stem Cell, Liu et al. (2009) show that p53 also plays a role in regulating hematopoietic stem cell quiescence.
Medical subject headings
- Hematopoietic Stem Cells
- Tumor Suppressor Protein p53