Exposing hidden dimensions of embryonic stem cell cycle control.

Dalton, Stephen · Cell Stem Cell · 2009

basic_science · Level V

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Abstract

In a recent issue of Nature Genetics, Wang and colleagues (2008) describe a mechanism for how the mir-290 microRNA cluster regulates the cell cycle of murine embryonic stem cells. A focal point of this regulation is the cyclin-dependent kinase inhibitor p21(Cip1).

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