SCARF: maximizing next-generation EST assemblies for evolutionary and population genomic analyses.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19129211.
- Also identified by DOI 10.1093/bioinformatics/btp011.
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Abstract
Scaffolded and Corrected Assembly of Roche 454 (SCARF) is a next-generation sequence assembly tool for evolutionary genomics that is designed especially for assembling 454 EST sequences against high-quality reference sequences from related species. The program was created to knit together 454 contigs that do not assemble during traditional de novo assembly, using a reference sequence library to orient the 454 sequences. SCARF is freely available at http://msbarker.com/software.htm, and is released under the open source GPLv3 license (http://www.opensource.org/licenses/gpl-3.0.html.
Medical subject headings
- Evolution, Molecular
- Expressed Sequence Tags
- Genome
- Genomics
- Software