A systems approach to analysis of molecular complexity in breast cancer.

Hennessy, Bryan T; Gonzalez-Angulo, Ana Maria; Carey, Mark S; Mills, Gordon B · Clin Cancer Res · 2009

editorial · Level V

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Abstract

In this issue of Clinical Cancer Research, Andre et al. apply high-resolution arrays to elucidate copy number anomalies in breast cancer. They identify distinct copy number anomaly patterns in different breast cancer subtypes that implicate a number of genes as potential therapeutic targets and as potential markers of therapy responsiveness.

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