Case study of the month. Complete histologic remission after sunitinib neoadjuvant therapy in T3b renal cell carcinoma.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 19150171.
- Also identified by DOI 10.1016/j.eururo.2008.12.036.
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Abstract
The authors present the first case report of complete histologic remission after neoadjuvant sunitinib treatment on primary renal tumour and vena cava thrombus. A 78-yr-old woman with an Eastern Cooperative Oncology Group (ECOG) score of 0 presented with a T3b renal tumour. She refused surgical treatment but agreed to percutaneous biopsy and medical treatment. A Fuhrman III renal cell carcinoma was histologically confirmed on percutaneous biopsy, and sunitinib treatment was administered over 6 mo. A significant objective response was observed for tumour size and thrombus. The patient finally accepted surgical treatment. Pathologic examination concluded with a complete response of primary tumour and thrombus.
Medical subject headings
- Carcinoma, Renal Cell
- Indoles
- Kidney Neoplasms
- Neoadjuvant Therapy
- Pyrroles