Pedunculopontine nucleus stimulation induces monocular oscillopsia.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 19151020.
- Also identified by DOI 10.1136/jnnp.2008.146472.
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Abstract
Two patients with Parkinson's disease with pedunculopontine nucleus (PPN) stimulation for gait impairments reported "trembling vision" during the setting of the electrical parameters, although there was no clinically observable abnormal eye movement. Oculomotor recordings revealed frequency locked voltage dependent vertical or oblique movements of the eye ipsilateral to the active contact, suggesting current spreading to the mesencephalic oculomotor fibres. These results emphasise the difficulty of stimulating this mesencephalic region.
Medical subject headings
- Antiparkinson Agents
- Eye Movements
- Gait Disorders, Neurologic
- Levodopa
- Mesencephalon
- Oculomotor Nerve Diseases
- Parkinson Disease
- Pedunculopontine Tegmental Nucleus
- Vision, Monocular