Pregnancy in true hermaphrodites and all male offspring to date.

Abstract

There are 11 reported cases of pregnancy in true hermaphrodites, but none with advanced genetic testing. All known fetuses have been male. A true hermaphrodite with a spontaneous pregnancy prenatally known to have a remaining portion of a right ovotestis, delivered a male neonate. The mother has a 46, XX karyotype with polymerase chain reaction demonstrating low levels of the Yq12 sequence. Postpartum androgen levels were normal. Partial removal of testicular tissue may enhance fertility in hermaphrodites, and there may be a genetic basis for the progeny to be male.