Autophagy SEPArates germline and somatic cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19167322.
- Also identified by DOI 10.1016/j.cell.2009.01.003 and PMC identifier 2782720.
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Abstract
Cellular determinants of the germline selectively accumulate in germ cell precursors and influence cell fate during early development in many organisms. Zhang et al. (2009) now report that targeted autophagy mediated by the SEPA-1 protein depletes germplasm proteins from somatic cells during early development of the nematode.
Medical subject headings
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Carrier Proteins