The PTP family photo album.

Tremblay, Michel L · Cell · 2009

review · Level V

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Abstract

Protein tyrosine phosphatases (PTPs) are central players in many biological processes. In this issue, Barr et al. (2009) analyze 22 different PTP structures to define their common and unique features. This effort provides key insights into the regulation of PTP activity that could lead to the development of new therapeutics.

Medical subject headings