Development of carcinoid tumour in hormonally treated adenocarcinoma of the prostate.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 19171417.
- Also identified by DOI 10.1016/j.eururo.2009.01.019.
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Abstract
We present the case of an 81-yr-old man with a prostatic adenocarcinoma and a metastatic carcinoid. Simultaneous occurrence of hormonally treated adenocarcinoma of the prostate and a carcinoid has been described before. The pathogenesis of this coincidence is largely unclear; however, androgen deprivation therapy might play a key role in neuroendocrine differentiation of adenocarcinoma cells. Early recognition of the carcinoid syndrome is crucial, as surgical cure is not possible after metastasis. We provide a brief review of recent literature.
Medical subject headings
- Adenocarcinoma
- Androgen Antagonists
- Anilides
- Antineoplastic Agents, Hormonal
- Carcinoid Tumor
- Liver Neoplasms
- Neoplasms, Multiple Primary
- Nitriles
- Prostatic Neoplasms
- Tosyl Compounds