Programmed subcellular release for studying the dynamics of cell detachment.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19182793.
- Also identified by DOI 10.1038/nmeth.1299 and PMC identifier 2882093.
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Abstract
Cell detachment is central to a broad range of physiopathological changes, but there are no quantitative methods to study this process. Here we report programmed subcellular release, a method for spatially and temporally controlled cellular detachment, and present quantitative results of the detachment dynamics of 3T3 fibroblasts at the subcellular level.
Medical subject headings
- Cell Adhesion
- Cytological Techniques