Delayed microbial cure of lymphogranuloma venereum proctitis with doxycycline treatment.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 19191633.
- Also identified by DOI 10.1086/597011.
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Abstract
Microbial cure of chlamydia proctitis (lymphogranuloma venereum [LGV] and non-LGV) with doxycycline treatment was evaluated by chlamydia DNA and RNA persistence in anal swab specimens. In LGV proctitis, RNA persisted for up to 16 days. In non-LGV chlamydia proctitis, DNA was undetectable after 7 days. These findings support the Centers for Disease Control and Prevention's treatment recommendation of a 21-day doxycycline regimen for LGV proctitis and a 7-day regimen for non-LGV chlamydia proctitis. Delayed microbial cure of LGV proctitis should be considered in improved treatment regimens.
Medical subject headings
- Anti-Bacterial Agents
- Chlamydia trachomatis
- Doxycycline
- Lymphogranuloma Venereum
- Proctitis