Balancing out the ends during iPSC nuclear reprogramming.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19200794.
- Also identified by DOI 10.1016/j.stem.2009.01.004.
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Abstract
In this issue of Cell Stem Cell, Marion et al. (2009) report that efficient production of iPSCs requires active telomerase, which allows the rejuvenation of telomeres to a state similar to that observed in embryonic stem cells, even in iPSCs generated from old donor cells.
Medical subject headings
- Cellular Reprogramming
- Pluripotent Stem Cells
- Telomerase
- Telomere