The MLLgnant consequences of reverting to an embryonic transcriptional program.
editorial · Level V
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- Record sourced from PubMed, PMID 19200795.
- Also identified by DOI 10.1016/j.stem.2009.01.008.
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Abstract
In this issue of Cell Stem Cell, Somervaille et al. (2009) have demonstrated convincingly that reversion to an embryonic transcriptional program through defective MLL gene expression contributes to the generation of myeloid leukemia stem cells.
Medical subject headings
- Gene Expression Regulation, Developmental
- Myeloid-Lymphoid Leukemia Protein
- Neoplastic Stem Cells
- Transcription, Genetic