Exploring pluripotency with chemical genetics.

Doble, Bradley W; Woodgett, James R · Cell Stem Cell · 2009

basic_science · Level V

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Abstract

In a recent issue of Chemistry & Biology, Bone et al. (2009) employed a chemical biology approach to probe the role of glycogen synthase kinase-3 (GSK-3), a key regulator of pluripotentiality, providing new insights and tools for modulating this process.

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