High mortality among patients with AIDS who received a diagnosis of tuberculosis in the first 3 months of antiretroviral therapy.

Koenig, Serena P; Riviere, Cynthia; Leger, Paul; Joseph, Patrice; Severe, Patrice; Parker, Kea; Collins, Sean; Lee, Erin et al. · Clin Infect Dis · 2009

retrospective_cohort · Level III

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Abstract

We analyzed mortality among 201 patients with AIDS and tuberculosis in Haiti. Patients who received a diagnosis of tuberculosis during the first 3 months after the initiation of antiretroviral therapy were 3.25 times more likely to die than were other patients with AIDS and tuberculosis. Failure to recognize active tuberculosis at initiation of antiretroviral therapy leads to increased mortality.

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