The pneumococcal pilus predicts the absence of Staphylococcus aureus co-colonization in pneumococcal carriers.

Regev-Yochay, Gili; Lipsitch, Marc; Basset, Alan; Rubinstein, Ethan; Dagan, Ron; Raz, Meir; Malley, Richard · Clin Infect Dis · 2009

case_control · Level III

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Abstract

The determinants of the negative association between Streptococcus pneumoniae and Stapylococcus aureus colonization are unknown. In this matched case-control study, the odds of co-colonization with S. aureus were significantly lower for individuals carrying a piliated versus a nonpiliated S. pneumoniae strain, suggesting the pilus may be a determinant of the negative association.

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