Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19209332.
- Also identified by DOI 10.1039/b813730g.
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Abstract
Most visual screens based on fluorescent markers are currently limited in throughput and accuracy. Here we present the first genetic screen of a mutagenized population of C. elegans in a microfluidic device. Animal handling streamlined by a microfluidic device and intuitive control software enabled the identification of novel mutants and a large screening speed.
Medical subject headings
- Caenorhabditis elegans
- Computers
- Microfluidics