Numerical study of the phase separation in binary lipid membrane containing protein inclusions under stationary shear flow.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19217626.
- Also identified by DOI 10.1016/j.jbiomech.2008.12.008.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The phase separation of lipids is believed to be responsible for the formation of lipid rafts in biological cell membrane. In the present work, a continuum model and a particle model are constructed to study the phase separation in binary lipid membrane containing inclusions under stationary shear flow. In each model, employing the cell dynamical system (CDS) approach, the kinetic equations of the confusion-advection process are numerically solved. Snapshot figures of the phase morphology are performed to intuitively display such phase evolving process. Considering the effects from both the inclusions and the shear flow, the time growth law of the characteristic domain size is discussed.
Medical subject headings
- Membrane Lipids
- Proteins