Bone age corresponds with chronological age at type 1 diabetes onset in youth.

Abstract

To our knowledge, only two controversial articles have reported the study of bone age at diagnosis in diabetic children. The aim of this study was to compare chronological age with bone age and to evaluate the impact of A1C on bone age in children at diagnosis of type 1 diabetes. In 496 diabetic children, height was measured at diagnosis and height SD score was calculated using the British 1990 growth reference. Bone age was determined according to the Greulich and Pyle method, and A1C levels were measured. Participants' height was normal for age and sex. No significant differences were found between chronological age and bone age, and there was no correlation between Delta (bone age - chronological age) and A1C. This study showed that height and bone maturation among diabetic children are normal for age and sex and independent of A1C at diagnosis of type 1 diabetes.