Calculation of strong and weak interactions in TDA1 and RangDP52 by the kernel energy method.

Huang, Lulu; Massa, Lou; Karle, Isabella; Karle, Jerome · Proc Natl Acad Sci U S A · 2009

basic_science · Level V

Where this comes from

Abstract

Using the Kernel Energy Method we apply ab initio quantum mechanics to study the relative importance of weak and strong interactions (including hydrogen bonds) in the crystal structures of the title compounds TDA1 and RangDP52. Perhaps contrary to widespread belief, in these compounds the weak interaction energies, because of their large number and cooperativity, can be significant to the binding energetics of the crystal, and thus also to its other properties.