Synthesis, characterization, and bioconjugation of fluorescent gold nanoclusters toward biological labeling applications.

Lin, Cheng-An J; Yang, Ting-Ya; Lee, Chih-Hsien; Huang, Sherry H; Sperling, Ralph A; Zanella, Marco; Li, Jimmy K; Shen, Ji-Lin et al. · ACS Nano · 2009

basic_science · Level V

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Abstract

Synthesis of ultrasmall water-soluble fluorescent gold nanoclusters is reported. The clusters have a decent quantum yield, high colloidal stability, and can be readily conjugated with biological molecules. Specific staining of cells and nonspecific uptake by living cells is demonstrated.

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