MicroRNAs and cancer: short RNAs go a long way.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19239879.
- Also identified by DOI 10.1016/j.cell.2009.02.005 and PMC identifier 3910108.
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Abstract
MicroRNAs (miRNAs) may be important regulators of gene expression. By modulating oncogenic and tumor suppressor pathways they could, in principle, contribute to tumorigenesis. Consistent with this hypothesis, recurrent genetic and epigenetic alterations of individual miRNAs are found in some tumors. Functional studies are now elucidating the mechanism of action of putative oncogenic and tumor suppressor miRNAs.
Medical subject headings
- MicroRNAs
- Neoplasms