Crawling out of the RNA world.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19239881.
- Also identified by DOI 10.1016/j.cell.2009.02.002.
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Abstract
Comparison of phylogenetically diverse ribonucleoprotein (RNP) enzymes and information about their biochemistry have stimulated hypotheses about their evolution. Instead of the canonical view, in which catalysis proceeds from ribozyme to RNP enzyme to protein enzyme, RNP enzymes and proteins are seen to share contemporary catalysis. Furthermore, the RNA components of RNP enzymes show no evidence of fading out but instead, in some cases, have elaborated new functions.
Medical subject headings
- Evolution, Molecular
- RNA, Catalytic
- Ribonucleoproteins